Traditional Remedies for HIV-Related Gastrointestinal Issues: A Focus on Medicinal Plants

Ngugi Mwaura J.

School of Natural and Applied Sciences Kampala International University Uganda

ABSTRACT

The Human Immunodeficiency Virus (HIV) remains a major global health challenge, particularly in sub-Saharan Africa, where access to antiretroviral therapy (ART) is limited, and gastrointestinal (GI) complications are prevalent. These GI disorders, often exacerbated by HIV infection and HAART regimens, compromise patient nutrition, immunity, and quality of life. In response, many communities turn to traditional medicine, particularly plant-based remedies, to manage these issues. This review explores the ethnobotanical, pharmacological, and clinical dimensions of medicinal plants used for HIV-related GI symptoms in Southern Africa. It examines specific plant species such as Sutherlandia frutescens, Aloe ferox, and Myrsine africana, highlighting their bioactive compounds, traditional uses, preparation methods, and proposed mechanisms of action. While preliminary scientific evaluations show promise, concerns remain regarding the safety, efficacy, and compatibility of these remedies with ART. This paper emphasizes the importance of integrative healthcare strategies that bridge traditional knowledge and biomedical science to enhance holistic HIV care and address persistent GI complications.

Keywords: HIV/AIDS, gastrointestinal disorders, traditional medicine, medicinal plants, Southern Africa, antiretroviral therapy (ART), herbal remedies.

CITE AS: Ngugi Mwaura J. (2025). Traditional Remedies for HIV-Related Gastrointestinal Issues: A Focus on Medicinal Plants. IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS 10(1):44-51. https://doi.org/10.59298/IDOSR/JBBAF/2025/1014451