Nanotechnology-Driven Drug Delivery Systems for Obesity Management

Serunjogi Ruth

Department of Clinical Pharmacy Kampala International University Uganda

Email: ruth.serunjogi@studwc.kiu.ac.ug

ABSTRACT

Obesity is a growing global epidemic, associated with diabetes, cardiovascular disease, cancer, and diminished life expectancy. Pharmacological treatments are often limited by poor bioavailability, low target specificity, and systemic toxicity. Nanotechnology offers innovative drug delivery solutions, improving solubility, stability, biodistribution, and therapeutic precision. Nanocarriers including liposomes, polymeric nanoparticles, dendrimers, micelles, and lipid-based systems have demonstrated potential for encapsulating anti-obesity drugs, nutraceuticals, and genetic material. These advances can enhance efficacy while minimizing adverse effects. This review explores the role of nanotechnology in obesity management, focusing on principles of design, recent advances, clinical translation, challenges, and future perspectives. Nanomedicine holds promise to revolutionize obesity therapy, though safety, manufacturing, and regulatory hurdles must be addressed.

Keywords: Obesity, Nanotechnology, Drug delivery, Nanocarriers, Therapeutics

CITE AS: Serunjogi Ruth (2025). Nanotechnology-Driven Drug Delivery Systems for Obesity Management. IDOSR JOURNAL OF EXPERIMENTAL SCIENCES 11(2): 24-30. https://doi.org/10.59298/IDOSR/JES/112.2430